Break Imaging Barriers for Renewed Understanding of Bone Microstructures

Struggle to observe intricate vascular and cellular networks embedded inside dense mandibular bone? Our state-of-the-art tissue clearing and 3D imaging technology non-destructively exposes the microenvironmental landscape within hard bone tissues via dual-color labeling:

YOYO (Blue): Nucleus staining delineates dense cellular distribution and spatial framework within mandibular bone and quantifies global cellular density.

Lectin (Red): Glycoprotein-specific labeling highlights vascular networks, visualizing hidden microvascular systems inside mineralized bone tissues in full 3D space.