Late-Stage Mouse Embryo: Whole-Embryo 3D Mapping Decodes the Spatiotemporal Rules of Neural Development

The developing nervous system follows sophisticated spatiotemporal regulatory patterns, which can only be partially captured by traditional tissue sections. We perform whole-embryo immunofluorescence staining to label neural structures (cyan) coupled with quantitative rendering, and reconstruct brain-spinal cord anatomical models (pink). Combined with the DeepSight 3D Lightsheet Microscope, complete 3D topological maps of embryonic neural networks are acquired. High-precision 3D modeling visualizes the assembly logic of neural circuits from gross anatomy down to fine local structures. The acquired spatial datasets support research on congenital malformation mechanisms, regenerative medicine efficacy assessment and high-throughput drug screening, driving developmental biology into a full panoramic imaging era.

3D Panoramic Visualization: Reveal the Microvascular Lifeline during Cerebrovascular Development in E16.5 Mouse Embryos

Wish to directly observe the elaborate construction of embryonic cerebral vascular networks in early life? Advanced tissue clearing and 3D imaging technologies non-invasively reconstruct intact panoramic vascular architectures inside E16.5 embryonic mouse brains.

E8小鼠胚胎膨胀样品（细胞核&Lectin阳性细胞）

采用锘海组织膨胀试剂盒和LS18 光片显微镜6.3X倍率成像